Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(GFAP-cre/PGR*)2Kdmc
Name:	transgene insertion 2, Ken D McCarthy
MGI ID:	MGI:3712448
Synonyms:	CrePR2, hGFAP-CrePR2, Tg(GFAP-cre)2Kdmc, Tg(GFAP-cre/PGR)2Kdmc
Transgene:	Tg(GFAP-cre/PGR*)2Kdmc  Location: unknown
Alliance:	Tg(GFAP-cre/PGR*)2Kdmc page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    mifepristone Mutation:    Insertion   Tg(GFAP-cre/PGR*)2Kdmc expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human GFAP (2670) Gfap  (MGI:95697)   Mutation details: Cre recombinase cDNA with the progesterone receptor was placed under the control of the human glial fibrillary acidic protein promoter. None of the 4 lines that expressed cre/PGR mRNA exhibited inducible recombinase activity after RU486 induction in crosses with reporter mice, so the lines were discontinued. (J:121777)

Activity:	Tissue activity of this recombinase allele
Driver:	GFAP (human) Summary of all recombinase alleles driven by GFAP. Alliance human GFAP gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:121777 Casper KB, et al., Characterization of astrocyte-specific conditional knockouts. Genesis. 2007 May;45(5):292-9
All:	1 reference(s)