Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Cyp19a1-cre)5909Gle
Name:	transgene insertion 5909, Gustavo Leone
MGI ID:	MGI:3712299
Transgene:	Tg(Cyp19a1-cre)5909Gle  Location: unknown
Alliance:	Tg(Cyp19a1-cre)5909Gle page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Cyp19a1-cre)5909Gle expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Cyp19a1   Mutation details: This transgene uses the cytochrome P450, family 19, subfamily a, polypeptide 1 promoter to drive expression of cre recombinase in the placenta. The transgene also contains an IRES-luciferase, the rabbit beta-globin intron and the SV-40 polyA signal. X-gal staining revealed that cre was expressed strongly in the skin and lens as well as the trilaminate layers of the placenta. Almost a third of the fetuses (29%) expressed cre throughout internal organs, including the heart, liver and brain. (J:121714)

Activity:	Tissue activity of this recombinase allele
Driver:	Cyp19a1 (species not specified) Summary of all recombinase alleles driven by Cyp19a1. Comparative matrix view of recombinase activities

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:121714 Wenzel PL, et al., Expression of Cre recombinase in early diploid trophoblast cells of the mouse placenta. Genesis. 2007 Mar;45(3):129-34
All:	2 reference(s)