Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccl12tm1Ifc
Name:	C-C motif chemokine ligand 12; targeted mutation 1, Israel F Charo
MGI ID:	MGI:3712151
Synonyms:	Ccl8/Ccl12tm1Ifc, Mcp-2-/Mcp-5-
Gene:	Ccl12  Location: Chr11:81992671-81994225 bp, + strand  Genetic Position: Chr11, 49.9 cM
Alliance:	Ccl12tm1Ifc page

Germline Transmission:	Earliest citation of germline transmission: J:121281
Parent Cell Line:	RF8 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A floxed neomycin resistance cassette was inserted into the chemokine (C-C motif) ligand 12 locus. This insertion disrupted the expression of this gene as well as chemokine (C-C motif) ligand 8. (J:121281)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccl12 Mutation:	16 strains or lines available

Original:	J:121281 Tsou CL, et al., Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest. 2007 Apr;117(4):902-9
All:	3 reference(s)