Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Nrp2tm1.1Mom
Name:	neuropilin 2; targeted mutation 1.1, Peter Mombaerts
MGI ID:	MGI:3712029
Synonyms:	Neuropilin-2-floxed, Nrp2flox
Gene:	Nrp2  Location: Chr1:62742476-62857851 bp, + strand  Genetic Position: Chr1, 31.35 cM, cytoband C2
Alliance:	Nrp2tm1.1Mom page

Germline Transmission:	Earliest citation of germline transmission: J:76686
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site 272 bp upstream of the translation initiation codon was introduced into exon 1 and a loxP-tauGFP FRT-flanked neo cassette was inserted 1 kb into intron 1 via homologous recombination. Heterozygous animals were crossed to an flp recombinase transgenic line for removal of the neo cassette. (J:76686)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nrp2 Mutation:	88 strains or lines available

Original:	J:76686 Walz A, et al., Aberrant sensory innervation of the olfactory bulb in neuropilin-2 mutant mice. J Neurosci. 2002 May 15;22(10):4025-35
All:	19 reference(s)