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Gene Expression Data
Assay Details
Assay
Reference: J:47920 Dattani MT, et al., Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse. Nat Genet. 1998 Jun;19(2):125-33
Assay type: RNA in situ
MGI Accession ID: MGI:3711938
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 probe5
Probe preparation: Antisense RNA
Results
Specimen 3a: embryonic day 8.5; Hesx1tm1Icar/Hesx1tm1Icar (more )
Note: This embryo contains 10 somites.
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 3a Expression is present in the anterior neural plate, but it the domain is substantially reduced in the mutant relative to that seen in the wild type. It is also asymmetric.
Specimen 3b: embryonic day 8.5 (more )
Note: This embryo contains 10 somites.
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 3b Expression is present in the anterior neural plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory