Gene Expression Data
Assay Details
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Assay
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Reference:
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J:73085
Dasen JS, et al., Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:3711537
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Gene symbol:
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Pomc
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Gene name:
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pro-opiomelanocortin-alpha
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Probe:
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POMC probe2
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2C e12.5 wt:
embryonic day 12.5
(more  )
Specimen
2C e12.5 wt:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: adenohypophysis |
Present |
Regionally restricted |
2C POMC e12.5 wt
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Expression is present in the corticotropes and melanotropes.
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| TS20: hypothalamus |
Present |
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2C POMC e12.5 wt
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Specimen
2C e12.5 Hesx1(-/-):
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Hesx1tm1Icar/Hesx1tm1Icar
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: adenohypophysis |
Absent |
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2C POMC e12.5 Hesx1-/-
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Expression is delayed in the mutant relative to wild type.
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| TS20: hypothalamus |
Absent |
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2C POMC e12.5 Hesx1-/-
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Expression is delayed in the mutant relative to wild type.
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Specimen
2C e14.5 wt:
embryonic day 14.5
(more )
Specimen
2C e14.5 wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: adenohypophysis |
Present |
Regionally restricted |
2C POMC e14.5 wt
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Expression is present in the corticotropes and melanotropes.
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Specimen
2C e14.5 Hesx1(-/-):
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Hesx1tm1Icar/Hesx1tm1Icar
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Age:
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embryonic day 14.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: adenohypophysis |
Present |
Regionally restricted |
2C POMC e14.5 Hesx1-/-
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Expression is present in the corticotropes and melanotropes in the rostral and caudal regions of the ventral pituitary.
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Specimen
6D e16.5:
embryonic day 16.5
(more )
Specimen
6D e16.5:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: adenohypophysis |
Present |
Regionally restricted |
6D POMC wt
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Expression is present in the corticotropes and melanotropes.
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Specimen
6E e16.5:
embryonic day 16.5
(more )
Specimen
6E e16.5:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: adenohypophysis |
Present |
Regionally restricted |
6E POMC wt
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Expression is present in the corticotropes and melanotropes.
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Analysis Tools