Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prpf19tm1Glri
Name:	pre-mRNA processing factor 19; targeted mutation 1, Johannes Grillari
MGI ID:	MGI:3711357
Synonyms:	Snev-
Gene:	Prpf19  Location: Chr19:10872595-10886923 bp, + strand  Genetic Position: Chr19, 7.33 cM
Alliance:	Prpf19tm1Glri page

Germline Transmission:	Earliest citation of germline transmission: J:121379
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1-6 were replaced by a lacZ reporter and a neomycin resistance cassette, both containing polyA signals and the latter also carrying a Rous sarcoma virus promoter. (J:121379)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prpf19 Mutation:	19 strains or lines available

Original:	J:121379 Fortschegger K, et al., Early embryonic lethality of mice lacking the essential protein SNEV. Mol Cell Biol. 2007 Apr;27(8):3123-30
All:	2 reference(s)