Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxp1tm1Rao
Name:	forkhead box P1; targeted mutation 1, Anjana Rao
MGI ID:	MGI:3711150
Synonyms:	Foxp-
Gene:	Foxp1  Location: Chr6:98902299-99499682 bp, - strand  Genetic Position: Chr6, 45.74 cM, cytoband E1
Alliance:	Foxp1tm1Rao page

Germline Transmission:	Earliest citation of germline transmission: J:112644
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A lacZ-neo was inserted to replace the sequence encoding the N-terminal two thirds of the protein, including the entire forkhead domain. The construct also removed the first translation start site to ensure efficient translation from the lacZ start codon. (J:112644)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxp1 Mutation:	75 strains or lines available

Original:	J:112644 Hu H, et al., Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol. 2006 Aug;7(8):819-26
All:	2 reference(s)