Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dlg1tm1Taki
Name:	discs large MAGUK scaffold protein 1; targeted mutation 1, Tetsu Akiyama
MGI ID:	MGI:3710242
Synonyms:	Dlgh1-
Gene:	Dlg1  Location: Chr16:31482261-31692174 bp, + strand  Genetic Position: Chr16, 22.4 cM
Alliance:	Dlg1tm1Taki page

Germline Transmission:	Earliest citation of germline transmission: J:121262
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: A neomycin resistance cassette was inserted into exon 3 in frame. RT-PCR confirmed insertion of the neo and absence of protein was demonstrated by Western blot analysis. (J:121262)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	34 assay results
In Structures Affected by this Mutation:	13 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dlg1 Mutation:	75 strains or lines available

Original:	J:121262 Iizuka-Kogo A, et al., Abnormal development of urogenital organs in Dlgh1-deficient mice. Development. 2007 May;134(9):1799-807
All:	3 reference(s)