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Ift88tm1Bky
Targeted Allele Detail
Summary
Symbol: Ift88tm1Bky
Name: intraflagellar transport 88; targeted mutation 1, Bradley K Yoder
MGI ID: MGI:3710185
Synonyms: Ift88fl, polarisLoxP
Gene: Ift88  Location: Chr14:57661519-57755393 bp, + strand  Genetic Position: Chr14, 30.1 cM
Alliance: Ift88tm1Bky page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117033
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sites were inserted to flank exons 4-6. (J:117033)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 20 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 12 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ift88 Mutation:  48 strains or lines available
References
Original:  J:117033 Haycraft CJ, et al., Intraflagellar transport is essential for endochondral bone formation. Development. 2007 Jan;134(2):307-16
All:  109 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory