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Tg(Npy-hrGFP)1Lowl
Transgene Detail
Summary
Symbol: Tg(Npy-hrGFP)1Lowl
Name: transgene insertion 1, Bradford B Lowell
MGI ID: MGI:3709190
Synonyms: NPY-GFP, Npy-hrGFP
Transgene: Tg(Npy-hrGFP)1Lowl  Location: unknown  
Alliance: Tg(Npy-hrGFP)1Lowl page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA bacterial artificial chromosome (BAC) was modified by inserting a humanized Renilla GFP (hrGFP, Stratagene) sequence into the translational start site of the mouse neuropeptide Y (Npy) gene. Correctly transformed and targeted bacteria were used to isolate the ~200 kb transgenic construct (called "NPY-GFP"). This NPY-GFP transgene was used for pronuclear injection into fertilized one-cell stage FVB embryos. Founder line 1 showing germline transmission was established. Brain tissues show GFP fluorescence when exposed to UV light. (J:120993)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:120993 Lowell BB, Generation of transgenic reporter mice with umanized Renilla GFP under control of the NPY promoter. MGI Direct Data Submission. 2007;
All:  133 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory