Dab1 Western blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:55691 Trommsdorff M, et al., Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell. 1999 Jun 11;97(6):689-701
Assay type:	Western blot
MGI Accession ID:	MGI:3707572
Gene symbol:	Dab1
Gene name:	disabled 1

Antibody:	anti-mDab(C)
Detection system:	Secondary antibody

Results

Image: 7_mDab1 (p80)

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	80 kDa (a)	Genetic Background	Mutant Allele(s)	Sex
+/+;+/+	P newborn	TS27: brain	Weak	Not Specified		Not Specified
+/-;+/-	P newborn	TS27: brain	Weak	involves: 129S6/SvEvTac * 129S7/SvEvBrd	Lrp8^tm1Her/Lrp8⁺, Vldlr^tm1Her/Vldlr⁺	Not Specified
-/-;+/+	P newborn	TS27: brain	Present (b)	involves: 129S7/SvEvBrd	Vldlr^tm1Her/Vldlr^tm1Her	Not Specified
+/+;-/-	P newborn	TS27: brain	Present (b)	involves: 129S6/SvEvTac	Lrp8^tm1Her/Lrp8^tm1Her	Not Specified
-/-;-/-	P newborn	TS27: brain	Strong (c)	involves: 129S6/SvEvTac * 129S7/SvEvBrd	Lrp8^tm1Her/Lrp8^tm1Her, Vldlr^tm1Her/Vldlr^tm1Her	Not Specified
-/-;-/-	P newborn	TS27: brain	Strong (c)	involves: 129S6/SvEvTac * 129S7/SvEvBrd	Lrp8^tm1Her/Lrp8^tm1Her, Vldlr^tm1Her/Vldlr^tm1Her	Not Specified

Notes:
(a) A larger non-specific band was noted by the authors.
(b) Expression level was increased 2- to 3-fold over wild type.
(c) Expression level was increased 13-fold over wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24