Dab1 Western blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:55691 Trommsdorff M, et al., Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell. 1999 Jun 11;97(6):689-701
Assay type:	Western blot
MGI Accession ID:	MGI:3707572
Gene symbol:	Dab1
Gene name:	disabled 1

Antibody:	anti-mDab(C)
Detection system:	Secondary antibody

Results

Image: 7_mDab1 (p80)

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	80 kDa (a)	Genetic Background	Mutant Allele(s)	Sex
+/+;+/+	P newborn	TS27: brain	Weak	Not Specified		Not Specified
+/-;+/-	P newborn	TS27: brain	Weak	involves: 129S6/SvEvTac * 129S7/SvEvBrd	Lrp8^tm1Her/Lrp8⁺, Vldlr^tm1Her/Vldlr⁺	Not Specified
-/-;+/+	P newborn	TS27: brain	Present (b)	involves: 129S7/SvEvBrd	Vldlr^tm1Her/Vldlr^tm1Her	Not Specified
+/+;-/-	P newborn	TS27: brain	Present (b)	involves: 129S6/SvEvTac	Lrp8^tm1Her/Lrp8^tm1Her	Not Specified
-/-;-/-	P newborn	TS27: brain	Strong (c)	involves: 129S6/SvEvTac * 129S7/SvEvBrd	Lrp8^tm1Her/Lrp8^tm1Her, Vldlr^tm1Her/Vldlr^tm1Her	Not Specified
-/-;-/-	P newborn	TS27: brain	Strong (c)	involves: 129S6/SvEvTac * 129S7/SvEvBrd	Lrp8^tm1Her/Lrp8^tm1Her, Vldlr^tm1Her/Vldlr^tm1Her	Not Specified

Notes:
(a) A larger non-specific band was noted by the authors.
(b) Expression level was increased 2- to 3-fold over wild type.
(c) Expression level was increased 13-fold over wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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