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Tg(Nphs1-cre)2Seq
Transgene Detail
Summary
Symbol: Tg(Nphs1-cre)2Seq
Name: transgene insertion 2, Susan E Quaggin
MGI ID: MGI:3703790
Synonyms: Nephrin-cre (KV)
Transgene: Tg(Nphs1-cre)2Seq  Location: unknown  
Alliance: Tg(Nphs1-cre)2Seq page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Nphs1-cre)2Seq expression driven by 1 gene
 
Mutation detailsA mouse Neph1 promoter fused to a cre recombinase gene was used for the transgene. A 4.125 kb fragment of the mouse Neph1 promoter was used to drive transgene expression in podocytes. This construct was previously used to produce Tg(Nphs1-cre)1Seq. (J:82024)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nphs1 (mouse)
Summary of all recombinase alleles driven by Nphs1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:82024 Eremina V, et al., Glomerular-specific gene excision in vivo. J Am Soc Nephrol. 2002 Mar;13(3):788-93
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory