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Gene Expression Data
Assay Details
Assay
Reference: J:62179 Zhao Z, et al., Expression of Dlx genes during the development of the murine dentition. Dev Genes Evol. 2000 May;210(5):270-5
Assay type: RNA in situ
MGI Accession ID: MGI:3703042
Gene symbol: Dlx2
Gene name: distal-less homeobox 2
Probe: Dlx2 probe10
Probe preparation: Antisense RNA
Results
Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present 1B
TS17: 1st branchial arch Present Regionally restricted 1B Expression is present in almost the entire mandibular arch along the distal-mesial axis, except for the most mesial region.
TS17: medial-nasal process Absent 1B There is no expression in the lingual side of the medial nasal process (the region from which upper incisors develop).
TS17: 1st branchial arch maxillary component Present Regionally restricted 1B

Specimen S1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mesenchyme Present S1C

Specimen S1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch maxillary component mesenchyme Present S1E

Specimen Not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: lower jaw incisor epithelium Present Regionally restricted Expression is present in the labial part of the dental lamina.
TS21: lower jaw molar epithelium Present Regionally restricted Expression is present in the labial part of the dental lamina.
TS21: upper jaw incisor epithelium Present Regionally restricted Expression is present in the labial part of the dental lamina.
TS21: upper jaw molar epithelium Present Regionally restricted Expression is present in the labial part of the dental lamina.
TS21: tooth mesenchyme Present

Specimen Not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS22: upper jaw molar enamel organ Present Regionally restricted Expression is present in the labial enamel epithelium.
TS22: tooth mesenchyme Present

Specimen Not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dental papilla Present

Specimen 3B: embryonic day 16.0-17.5 (more )
Note: This tooth is at late bell stage.
Structure Level Pattern Image Note
TS24: molar enamel organ Present 3B Expression is present in the inner and outer enamel epithelium, the stratum intermedium, and the cervical loop. It is expressed in preameloblasts.
TS24: cervical loop Present 3B
TS24: inner enamel epithelium Present 3B
TS24: outer enamel epithelium Present 3B
TS24: stratum intermedium Present 3B

Specimen 3B inset: embryonic day 16.0-17.5 (more )
Note: This tooth is at late bell stage.
Structure Level Pattern Image Note
TS24: molar enamel organ Present 3B inset Expression is present in the inner and outer enamel epithelium, the stratum intermedium, and the cervical loop. It is expressed in preameloblasts.
TS24: cervical loop Present 3B inset
TS24: inner enamel epithelium Present 3B inset
TS24: outer enamel epithelium Present 3B inset
TS24: stratum intermedium Present 3B inset

Specimen Not shown: embryonic day 16.0-17.0 (more )
Structure Level Pattern Image Note
TS24: lower jaw incisor Present

Specimen Not shown: postnatal (more )
Structure Level Pattern Image Note
TS28: molar Absent There is no expression in the first molars after birth.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory