About   Help   FAQ
Tg(Emx1-cre)3Ito
Transgene Detail
Summary
Symbol: Tg(Emx1-cre)3Ito
Name: transgene insertion 3, Shigeyoshi Itohara
MGI ID: MGI:3701619
Synonyms: Tg3
Transgene: Tg(Emx1-cre)3Ito  Location: unknown  
Alliance: Tg(Emx1-cre)3Ito page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Emx1-cre)3Ito expression driven by 1 gene
 
Mutation details: An Emx1 positive PAC clone frome the RPCI-21 PAC mouse genomic library (PAC-Emx1#1) was modified by the insertion of an NLS-Cre-poly(A) cassette into the NotI site by homologous recombination in bacteria. Two independent recombination events were identified. This transgenic line was generated from the PAC-Cre-B fragment and has 7-9 copies of the transgene. (J:88421)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Emx1 (mouse)
Summary of all recombinase alleles driven by Emx1.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Embryonic expression is first seen in the dorsal telencephalon at E10. Adult expression of this transgene is seen in the olfactory bulb, neocortex, piriform cortex, hippocampus and amygdala of the brain. Activity is primarily in excitatory neurons and astrocytes. Little or no activity is seen in inhibitory neurons. Expression is also seen in the thymus, stomach, testes, and some regions of the skin at 7-8 days of age.
References
Original:  J:88421 Iwasato T, et al., Dorsal telencephalon-specific expression of Cre recombinase in PAC transgenic mice. Genesis. 2004 Mar;38(3):130-8
All:  7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory