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Gene Expression Data
Assay Details
Assay
Reference: J:118610 Nicol X, et al., Role of the calcium modulated cyclases in the development of the retinal projections. Eur J Neurosci. 2006 Dec;24(12):3401-14
Assay type: RNA in situ
MGI Accession ID: MGI:3701516
Gene symbol: Adcy1
Gene name: adenylate cyclase 1
Probe: AC1 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Expression was considered to be significant when the signal was twice the background. Most of these results are quantified in Fig. 3.
Results
Specimen 1 E15: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: retina nuclear layer Present Regionally restricted 1A , 1A' Expression is present in the retinal ganglion cell layer; it is not present in the outer neuroblastic layer. This is one of the times with the highest expression level.
Specimen 1 P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 1B' , 1B This is one of the times with the highest expression level.
Specimen 1 P10: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 1C , 1C'
TS28: photoreceptor layer outer segment Present 1C' , 1C
Specimen 1 Adult: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present 1D , 1D' Expression is significantly reduced at this time. It is not detected in the ventral LGN.
Specimen 4 E15: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: thalamus Strong Non-Uniform 4A There is strong expression in the entire dorsal thalamus; expression is weaker in the ventral thalamus.
Specimen 4 P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: lateral geniculate nucleus Strong Non-Uniform 4B There is strong expression in the dorsal LGN; low levels of expression are detected in the ventral LGN.
Specimen 4 P10: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: lateral geniculate nucleus Strong Non-Uniform 4C There is strong expression in the dorsal LGN; low levels of expression are detected in the ventral LGN.
Specimen 4 Adult: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: lateral geniculate nucleus Present Non-Uniform 4D The level of expression in the dorsal LGN is the lowest of all the postnatal ages; low levels of expression are detected in the ventral LGN.
Specimen 5 E15: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: midbrain roof plate Strong Non-Uniform 5A There is strong expression in the inferior colliculus, and moderiate expression in the superior colliculus.
Specimen 5 P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: superior colliculus Strong Non-Uniform 5B There is strong expression in the inferior colliculus, and moderiate expression in the superior colliculus.
Specimen 5 P10: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: superior colliculus Strong Non-Uniform 5C There is strong expression in the inferior colliculus, and moderiate expression in the superior colliculus.
Specimen 5 Adult: postnatal month 2 (more )
Structure Level Pattern Image Note
TS28: superior colliculus Absent 5D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory