Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prdx3Gt(Betageo-puro)711Lex
Name:	peroxiredoxin 3; gene trap 711, Lexicon Genetics
MGI ID:	MGI:3700138
Synonyms:	Mer5-, PrxIII-
Gene:	Prdx3  Location: Chr19:60852504-60862976 bp, - strand  Genetic Position: Chr19, 56.52 cM
Alliance:	Prdx3Gt(Betageo-puro)711Lex page

Germline Transmission:	Earliest citation of germline transmission: J:118595
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector   Mutation details: A gene trap vector was integrated within the first intron. Western blot confirmed ablation of the locus. (J:118595)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prdx3 Mutation:	23 strains or lines available

Original:	J:118595 Li L, et al., Increased susceptibility of MER5 (peroxiredoxin III) knockout mice to LPS-induced oxidative stress. Biochem Biophys Res Commun. 2007 Apr 13;355(3):715-21
All:	5 reference(s)