Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Alms1L2131X Name: ALMS1, centrosome and basal body associated; L2131 MGI ID: MGI:3699224 Gene: Alms1  Location: Chr6:85564513-85679735 bp, + strand  Genetic Position: Chr6, 37.48 cM Alliance: Alms1L2131X page

Kidney abnormalities of Alms1L2131X/Alms1L2131X mice at 6 months of age Show the 3 phenotype image(s) involving this allele.

Strain of Origin:

C57BL/6

Allele Type:    Chemically induced (ENU) Mutation:    Nucleotide substitutions   Mutation details: This mutation causes premature truncation in exon 10, resulting in the coding of the N-terminal 2131 amino acids of the protein. (J:118221)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Alms1 Mutation:	149 strains or lines available

Original:	J:118221 Li G, et al., A Role for Alstrom Syndrome Protein, Alms1, in Kidney Ciliogenesis and Cellular Quiescence. PLoS Genet. 2007 Jan 5;3(1):e8
All:	1 reference(s)