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Tg(Mpz-Nrg1)34Slca
Transgene Detail
Summary
Symbol: Tg(Mpz-Nrg1)34Slca
Name: transgene insertion 34, Steven L Carroll
MGI ID: MGI:3514151
Synonyms: P0-GGFbeta3
Transgene: Tg(Mpz-Nrg1)34Slca  Location: unknown  
Alliance: Tg(Mpz-Nrg1)34Slca page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Mpz-Nrg1)34Slca expresses 1 gene
 
Mutation detailsThis transgene expresses the rat Nrg1 varient GGFbeta3 containing a common leucine polymorphism under the control of the mouse Mpz promoter. Transgene expression is directed to Schwann cells and was detected in the sciatic nerve. (J:84874)
Tumor Data
List all tumor models in MMHCdb carrying Tg(Mpz-Nrg1)34Slca
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:84874 Huijbregts RP, et al., Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells. J Neurosci. 2003 Aug 13;23(19):7269-80
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory