Tg(Mpz-Nrg1)34Slca
Transgene Detail
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Symbol: |
Tg(Mpz-Nrg1)34Slca |
Name: |
transgene insertion 34, Steven L Carroll |
MGI ID: |
MGI:3514151 |
Synonyms: |
P0-GGFbeta3 |
Transgene: |
Tg(Mpz-Nrg1)34Slca Location: unknown
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Alliance: |
Tg(Mpz-Nrg1)34Slca page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Mpz-Nrg1)34Slca expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
rat |
Nrg1 (112400) |
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Mutation details: This transgene expresses the rat Nrg1 varient GGFbeta3 containing a common leucine polymorphism under the control of the mouse Mpz promoter. Transgene expression is directed to Schwann cells and was detected in the sciatic nerve.
(J:84874)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:84874 Huijbregts RP, et al., Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells. J Neurosci. 2003 Aug 13;23(19):7269-80 |
All: |
3 reference(s) |
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