Tg(Pim1-E2F2)37Rebr
Transgene Detail
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| Symbol: |
Tg(Pim1-E2F2)37Rebr |
| Name: |
transgene insertion 37, Rene Bernards |
| MGI ID: |
MGI:3527141 |
| Synonyms: |
Eu-pp-E2F2, TEF2-37 |
| Transgene: |
Tg(Pim1-E2F2)37Rebr Location: unknown
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| Alliance: |
Tg(Pim1-E2F2)37Rebr page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Pim1-E2F2)37Rebr expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
E2F1 (1869) |
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Tg(Pim1-E2F2)37Rebr expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Pim1 (MGI:97584) |
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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A human E2F2 cDNA was cloned downstream of a murine Pim1 promoter in which a duplicated immunoglobulin heavy chain enhancer sequence was inserted. The polyA sequence was contributed by the Molony murine leukemia virus.
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| Original: |
J:88864 Scheijen B, et al., High incidence of thymic epithelial tumors in E2F2 transgenic mice. J Biol Chem. 2004 Mar 12;279(11):10476-83 |
| All: |
1 reference(s) |
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Analysis Tools
