Tg(Pim1-E2F1)5Rebr
Transgene Detail
|
|
| Symbol: |
Tg(Pim1-E2F1)5Rebr |
| Name: |
transgene insertion 5, Rene Bernards |
| MGI ID: |
MGI:3527138 |
| Synonyms: |
Eu-pp-E2F1, TEF1-5 |
| Transgene: |
Tg(Pim1-E2F1)5Rebr Location: unknown
|
| Alliance: |
Tg(Pim1-E2F1)5Rebr page
|
|
|
|
| Transgene Type: |
|
Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(Pim1-E2F1)5Rebr expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
E2F1 (1869) |
|
|
|
| |
|
Tg(Pim1-E2F1)5Rebr expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Pim1 (MGI:97584) |
|
|
| |
|
Mutation details: A human E2F1 cDNA was cloned downstream of a murine Pim1 promoter in which a duplicated Ig heavy chain enhancer sequence was inserted. The polyA sequence was contributed by the Molony murine leukemia virus.
(J:88864)
|
|
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:88864 Scheijen B, et al., High incidence of thymic epithelial tumors in E2F2 transgenic mice. J Biol Chem. 2004 Mar 12;279(11):10476-83 |
| All: |
1 reference(s) |
|
Analysis Tools
