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Gene Expression Data
Assay Details
Assay
Reference: J:116140 Nam JS, et al., Dynamic expression of R-spondin family genes in mouse development. Gene Expr Patterns. 2007 Jan;7(3):306-12
Assay type: RNA in situ
MGI Accession ID: MGI:3698281
Gene symbol: Rspo4
Gene name: R-spondin 4
Probe: Rspo4 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen Not shown: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Absent

Specimen 1E: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future brain Weak Regionally restricted 1E Expression is in the groove of the neural fold.

Specimen 1I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Weak 1I
TS15: heart Strong 1I
TS15: limb Strong 1I

Specimen 1M: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 1M Expression is widespread.

Specimen 2D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: diencephalon lateral wall Strong Regionally restricted 2D Expression is in the ependymal layer of the dorsal neural tube.

Specimen 2H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: heart Strong 2H
TS15: limb Strong 2H

Specimen 2L: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present Regionally restricted 2L Expression is in the surrounding cells of the Rathke's pouch.

Specimen Not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: heart Present

Specimen 3D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud ectoderm Present Regionally restricted 3D Expression is in the posterior and anterior region of the surface ectoderm of limb buds.

Specimen 3H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud ectoderm Present Regionally restricted 3H Expression is in the posterior and anterior region of the surface ectoderm of limb buds.

Specimen 3L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb Absent 3L

Specimen 3P: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hand Strong 3P Expression is in the apical ectodermal ridge.

Specimen 4D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tooth mesenchyme Strong 4D

Specimen 4H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: humerus Strong Regionally restricted 4H Expression is in the cartilage.

Specimen 4L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: dorsal root ganglion Strong 4L

Specimen 4P: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: thymus primordium Strong 4P

Specimen 4T: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord Strong Regionally restricted 4T Expression is in most of the spinal cord except the most ventral region.

Specimen 4X: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: humerus Present Regionally restricted 4X Expression is in the prehypertrophic and hypertrophic chondrocytes of long bones.

Specimen Table 1 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: medulla oblongata Weak

Specimen Table 1 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: skeleton Moderate Regionally restricted Expression is in the long bones.
TS23: cranium Weak
TS23: dorsal root ganglion Weak
TS23: facial bone primordium Weak
TS23: medulla oblongata Weak
TS23: skin Weak
TS23: spinal cord Weak
TS23: thymus primordium Weak
TS23: tooth Weak
TS23: vertebra Weak

Specimen Table 1 E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: tooth Moderate
TS25: skeleton Moderate Regionally restricted Expression is in the long bones.
TS25: vertebra Moderate
TS25: cranium Weak
TS25: dorsal root ganglion Weak
TS25: facial bone Weak
TS25: medulla oblongata Weak
TS25: skin Weak
TS25: spinal cord Weak
TS25: thymus Weak


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory