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Tg(Fabp1-OLIG2)#Flds
Transgene Detail
Summary
Symbol: Tg(Fabp1-OLIG2)#Flds
Name: transgene insertion #, Alan P Fields
MGI ID: MGI:3531329
Synonyms: PKC betaII
Transgene: Tg(Fabp1-OLIG2)#Flds  Location: unknown  
Alliance: Tg(Fabp1-OLIG2)#Flds page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Fabp1-OLIG2)#Flds expresses 1 gene
 
Mutation detailsA cDNA fragment encoding a full length human PKC BetaII (OLIG2) protein was cloned downstream of the rat Fabp1 promoter. The polyA sequence was from the SV40 large T antigen. Depending on the founder line anywhere from six to 31 copies of the transgene were incorporated into the genome. (J:55331)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:68515 Gokmen-Polar Y, et al., Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis. Cancer Res. 2001 Feb 15;61(4):1375-81
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory