Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bcl3tm1Rsch
Name:	B cell leukemia/lymphoma 3; targeted mutation 1, Roland M Schmid
MGI ID:	MGI:3695737
Synonyms:	Bcl-3-
Gene:	Bcl3  Location: Chr7:19542387-19556691 bp, - strand  Genetic Position: Chr7, 9.95 cM
Alliance:	Bcl3tm1Rsch page

Germline Transmission:	Earliest citation of germline transmission: J:116724
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced a fragment of the locus encoding the ankyrin repeat sequences 1-4. (J:116724)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl3 Mutation:	56 strains or lines available

Original:	J:116724 Riemann M, et al., The IkappaB protein Bcl-3 negatively regulates transcription of the IL-10 gene in macrophages. J Immunol. 2005 Sep 15;175(6):3560-8
All:	2 reference(s)