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Gfi1tm3(Gfib1)Tmo
Targeted Allele Detail
Summary
Symbol: Gfi1tm3(Gfib1)Tmo
Name: growth factor independent 1 transcription repressor; targeted mutation 3, Tarik Moroy
MGI ID: MGI:3695403
Synonyms: Gfi1:Gfi1b
Gene: Gfi1  Location: Chr5:107864521-107873671 bp, - strand  Genetic Position: Chr5, 52.23 cM
Alliance: Gfi1tm3(Gfib1)Tmo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:116870
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
    The coding region was replaced with growth factor independent 1B cDNA. (J:116870)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gfi1 Mutation:  31 strains or lines available
References
Original:  J:116870 Fiolka K, et al., Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Rep. 2006 Mar;7(3):326-33
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory