Gene Expression Data
Assay Details
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Assay
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Reference:
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J:48924
Murgia C, et al., Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain. EMBO J. 1998 Jul 15;17(14):3940-51
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3694729
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Gene symbol:
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Cdkn1b
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Gene name:
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cyclin dependent kinase inhibitor 1B
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Antibody:
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Anti-p27Kip
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Detection system:
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horseradish peroxidase
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Results
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Specimen
7B beta4 WT:
embryonic day 18.5
(more  )
Specimen
7B beta4 WT:
(close  )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: duodenum |
Present |
Regionally restricted |
7B WT
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Expression was not detected in the enterocytes of intervillar spaces and the basal portion of villi. The intervillar spaces contained 15.6 immunonegative cells.
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Specimen
7B beta4 TL:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Itgb4tm1Fgg/Itgb4tm1Fgg
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: duodenum |
Present |
Regionally restricted |
7B TL
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Immunostaining extended to the base of villi with frequent immunopositive cells in the intervillar spaces. There were fewer (9.7) immunonegative cells in the intervillar spaces compared to wild type.
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Analysis Tools
