Tg(KRT14-HPV16E7)2341Plam
Transgene Detail
|
|
| Symbol: |
Tg(KRT14-HPV16E7)2341Plam |
| Name: |
transgene insertion 2341, Paul F Lambert |
| MGI ID: |
MGI:3514319 |
| Synonyms: |
2341, K14HPV16E7 |
| Transgene: |
Tg(KRT14-HPV16E7)2341Plam Location: unknown
|
| Alliance: |
Tg(KRT14-HPV16E7)2341Plam page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: This transgene contains a HPV16 fragment (nt79-883) encompassing both the E6 and E7 genes along with promoter, 3' UTR and polyA sequences from human KRT14. Only E7 was expressed due to the presence of a translation termination linker in the N terminal region of the E6 gene. Transgene expression is targeted to epithelial tissues. Mice derived from this founder had 2-3 copies of the transgene.
(J:86018)
|
|
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:86018 Herber R, et al., Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene. J Virol. 1996 Mar;70(3):1873-81 |
| All: |
1 reference(s) |
|
Analysis Tools
