Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Fabp1-OLIG2)54Flds
Name:	transgene insertion 54, Alan P Fields
MGI ID:	MGI:3531327
Synonyms:	line 54, PKC BetaII
Transgene:	Tg(Fabp1-OLIG2)54Flds  Location: unknown
Alliance:	Tg(Fabp1-OLIG2)54Flds page

Strain of Origin:

(C57BL/6J x C3H/HeJ)F2

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Fabp1-OLIG2)54Flds expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human OLIG2 (10215) Olig2  (MGI:1355331)   Mutation details: A cDNA fragment encoding a full length human PKC BetaII (OLIG2) protein was cloned downstream of the rat Fabp1 promoter. The polyA sequence was from the SV40 large T antigen. Six copies of the transgene were incorporated into the genome. (J:55331)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:55331 Murray NR, et al., Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis. J Cell Biol. 1999 May 17;145(4):699-711
All:	3 reference(s)