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Gene Expression Data
Assay Details
Assay
Reference: J:80673 Bergo MO, et al., Defining the importance of phosphatidylserine synthase 2 in mice. J Biol Chem. 2002 Dec 6;277(49):47701-8
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3693917
Gene symbol: Ptdss2
Gene name: phosphatidylserine synthase 2
Reporter: lacZ
Direct Detection
Assay notes: The cryostat sections were fixed with 2% formaldehyde in phosphate-buffered saline supplemented with 0.2% glutaraldhyde.
Results
Specimen 6A: embryonic day 20.0; Ptdss2Gt(KST314)Byg/Ptdss2Gt(KST314)Byg (more )
Structure Level Pattern Image Note
TS26: brown fat Strong 6A This fat was located over the dorsal thoracic cage.
TS26: peripheral nervous system Strong 6A Expression is present in the peripheral nerves.
Specimen 6C: postnatal adult; Ptdss2Gt(KST314)Byg/Ptdss2Gt(KST314)Byg (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 6D , 6C Expression is confined to the neurons.
TS28: cerebellum Purkinje cell layer Present 6C , 6D Expression is particularly prominent in this area.
Specimen 6E: postnatal adult; Ptdss2Gt(KST314)Byg/Ptdss2Gt(KST314)Byg (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 6E Expression is present in the pyramidal neurons.
Specimen 6F: postnatal adult; Ptdss2Gt(KST314)Byg/Ptdss2Gt(KST314)Byg (more )
Structure Level Pattern Image Note
TS28: myometrium Strong 6F
Specimen 7A: postnatal month 6; Ptdss2Gt(KST314)Byg/Ptdss2Gt(KST314)Byg (more )
Note: This animal has apparently normal looking testes.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Strong 7A There is intense staining of the Sertoli cells of the spermatic ducts.
TS28: Leydig cell Leydig cell Present 7A There is punctate staining within the Leydig cells, but its intensity is less than that found in the Sertoli cells.
TS28: spermatocyte Absent 7A No staining of spermatogonia or spermatocytes.
TS28: spermatogonium Absent 7A No staining of spermatogonia or spermatocytes.
Specimen 7B: postnatal month 6; Ptdss2Gt(KST314)Byg/Ptdss2Gt(KST314)Byg (more )
Note: This animal has atrophic testes.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Strong 7B There is intense staining of the Sertoli cells even though the spermatic ducts of this animal are devoid of spermatagonia.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory