Gene Expression Data
Assay Details
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Assay
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Reference:
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J:60748
Yang J, et al., Mekk3 is essential for early embryonic cardiovascular development. Nat Genet. 2000 Mar;24(3):309-13
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3693892
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Gene symbol:
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Pecam1
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Gene name:
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platelet/endothelial cell adhesion molecule 1
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Results
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Specimen
3g:
embryonic day 9.5
(more  )
Specimen
3g:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3h:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Map3k3tm1Bisu/Map3k3tm1Bisu
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: extraembryonic vascular system |
Present |
Regionally restricted |
3h
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Expression was detected in endothelial cells of blood vessels as in wild type, but the mutant yolk sacs had a blood vessel defect.
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Specimen
4e:
embryonic day 10.0
(more )
Specimen
4e:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
4f:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Map3k3tm1Bisu/Map3k3tm1Bisu
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
4g:
embryonic day 9.5
(more )
Note: Fig. 4i and 4k are higher magnification images of Fig. 4g.
Specimen
4g:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Fig. 4i and 4k are higher magnification images of Fig. 4g.
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Specimen
4h:
embryonic day 9.5; Map3k3tm1Bisu/ Map3k3tm1Bisu
(more )
Note: Fig. 4j and 4l are higher magnification images of Fig. 4h.
Specimen
4h:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Map3k3tm1Bisu/Map3k3tm1Bisu
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Age:
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embryonic day 9.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Fig. 4j and 4l are higher magnification images of Fig. 4h.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: blood vessel |
Present |
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4j
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4l
,
4h
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Expression in embryonic blood vessels was detected as in wild type, but defects were noted in the brain and intersomitic blood vessels.
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Analysis Tools