Tg(KRT5-SMO)#Fjs
Transgene Detail
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| Symbol: |
Tg(KRT5-SMO)#Fjs |
| Name: |
transgene insertion #, Frederic J de Sauvage |
| MGI ID: |
MGI:3525056 |
| Synonyms: |
SMO, SMO-WT, WT |
| Transgene: |
Tg(KRT5-SMO)#Fjs Location: unknown
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| Alliance: |
Tg(KRT5-SMO)#Fjs page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(KRT5-SMO)#Fjs expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
SMO (6608) |
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Tg(KRT5-SMO)#Fjs expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
KRT5 (3852) |
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Mutation details: The wildtype human SMO cDNA was cloned downstream of the human KRT5 promoter. Enhancer and polyA sequences were contributed by SV40. Transgene expression was observed in the basal cell layer in transgenic skin. Postnatal data were not available for this allele.
(J:87306)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:87306 Xie J, et al., Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature. 1998 Jan 1;391(6662):90-2 |
| All: |
1 reference(s) |
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Analysis Tools
