Tg(MSCV-BCR/ABL*P230)13Kti
Transgene Detail
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| Symbol: |
Tg(MSCV-BCR/ABL*P230)13Kti |
| Name: |
transgene insertion 13, Koiti Inokuchi |
| MGI ID: |
MGI:3527200 |
| Synonyms: |
no. 13, P230BCR/ABL no. 13, PCMV-P230BCR/ABL |
| Transgene: |
Tg(MSCV-BCR/ABL*P230)13Kti Location: unknown
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| Alliance: |
Tg(MSCV-BCR/ABL*P230)13Kti page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: This transgene expresses the P230 variant of the human derived BCR/ABL fusion protein, involving BCR exon 19 fused to ABL exon 2. This gene was cloned downstream of the LTR from the Murine Stem Cell Virus (MSCV), which was referred to in this paper as PCMV. 10 copies of the transgene were incorporated into the genome. This transgene was not propagated beyond the founder mouse.
(J:84626)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:84626 Inokuchi K, et al., Myeloproliferative disease in transgenic mice expressing P230 Bcr/Abl: longer disease latency, thrombocytosis, and mild leukocytosis. Blood. 2003 Jul 1;102(1):320-3 |
| All: |
1 reference(s) |
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Analysis Tools
