Tg(H2-k-Polb/Sh)8Cca
Transgene Detail
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| Symbol: |
Tg(H2-k-Polb/Sh)8Cca |
| Name: |
transgene insertion 8, Christophe Cazaux |
| MGI ID: |
MGI:3525161 |
| Synonyms: |
H-2K/Pol Beta, Tg 8a |
| Transgene: |
Tg(H2-k-Polb/Sh)8Cca Location: unknown
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| Alliance: |
Tg(H2-k-Polb/Sh)8Cca page
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| Strain of Origin: |
(CBA x C57BL/6)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(H2-k-Polb/Sh)8Cca expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Polb (MGI:97740) |
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Mutation details: The promoter for the murine MHC class I H-2K gene directed the expression of a rat Polb cDNA fragment to the thymus. Enhancer and polyA sequences were donated by the rabbit Beta-globin gene. Transgene expression was detected in the thymus, but not in the spleen, kidney, heart, lung, liver, intestine, or testis.
(J:90141)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Hemizygous transgenic mice show no phenotype, while homozygous mice (25/69) showed premature death due to unknown causes.
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| Original: |
J:90141 Bergoglio V, et al., Evidence of finely tuned expression of DNA polymerase beta in vivo using transgenic mice. FEBS Lett. 2004 May 21;566(1-3):147-150 |
| All: |
1 reference(s) |
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Analysis Tools
