Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Nkx3-1tm1(cre)Wez
Name:	NK3 homeobox 1; targeted mutation 1, Warren E Zimmer
MGI ID:	MGI:3689997
Synonyms:	Nkx3.1-cre
Gene:	Nkx3-1  Location: Chr14:69428141-69432107 bp, + strand  Genetic Position: Chr14, 36.02 cM
Alliance:	Nkx3-1tm1(cre)Wez page

Germline Transmission:	Earliest citation of germline transmission: J:114573
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Nkx3-1tm1(cre)Wez expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Nkx3-1 (MGI:97352)   Mutation details: A cre-PGK-neo cassette was inserted into the second exon of the locus, deleting ~630 bp spanning from the homeodomain to the end of the protein. (J:114573)

Activity:	Tissue activity of this recombinase allele
Driver:	Nkx3-1 (mouse) Summary of all recombinase alleles driven by Nkx3-1. Alliance mouse Nkx3-1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nkx3-1 Mutation:	39 strains or lines available

Original:	J:114573 Stanfel MN, et al., Expression of an Nkx3.1-CRE gene using ROSA26 reporter mice. Genesis. 2006 Nov;44(11):550-5
All:	1 reference(s)