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Gene Expression Data
Assay Details
Assay
Reference: J:113117 Nam JS, et al., Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem. 2006 May 12;281(19):13247-57
Assay type: RNA in situ
MGI Accession ID: MGI:3687286
Gene symbol: Rspo3
Gene name: R-spondin 3
Probe: Cristin1/Rspondin3 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1B +/-: embryonic day 9.5; Msgn1tm1Wb/Msgn1+ (more )
Structure Level Pattern Image Note
TS15: tail Strong 1B +/-
TS15: embryo Present Regionally restricted 1B +/- Expression is in the primitive streak.
TS15: neural tube Present Regionally restricted 1B +/- Expression is in the dorsal neural tube.
TS15: future forebrain Present 1B +/-
TS15: migrating neural crest Present 1B +/-

Specimen 1B -/-: embryonic day 9.5; Msgn1tm1Wb/Msgn1tm1Wb (more )
Structure Level Pattern Image Note
TS15: tail Very strong 1B -/- The expression domain was expanded in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory