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Gene Expression Data
Assay Details
Assay
Reference: J:80666 Smits P, et al., The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90
Assay type: RNA in situ
MGI Accession ID: MGI:3687206
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Cbfa1 cDNA7
Probe preparation: Antisense labelled with S35
Results
Specimen 7 Cbfa1 top: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted 7_Cbfa1 top panel Expression was detected in prehypertrophic and hypertrophic chondrocytes but not in chondroblasts.

Specimen 7 Cbfa1 bottom: embryonic day 16.5; Sox5tm1Vlf/Sox5tm1Vlf, Sox6tm1Vlf/Sox6tm1Vlf (more )
Structure Level Pattern Image Note
TS24: humerus Strong Regionally restricted 7_Cbfa1 bottom panel Expression was detected throughout the entire mutant cartilage.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory