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Gene Expression Data
Assay Details
Assay
Reference: J:80666 Smits P, et al., The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90
Assay type: RNA in situ
MGI Accession ID: MGI:3687127
Gene symbol: Col1a1
Gene name: collagen, type I, alpha 1
Probe: pMCol1a1-1
Probe preparation: Antisense labelled with S35
Results
Specimen 4B left: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cervical vertebral cartilage condensation Absent 4B Col1a1 wild type
TS20: thoracic vertebral cartilage condensation Absent 4B Col1a1 wild type
TS20: embryo Strong Regionally restricted 4B Col1a1 wild type Expression was intense in tissues surrounding the prevertebral cartilages.
Specimen 4B right: embryonic day 12.5; Sox5tm1Vlf/Sox5tm1Vlf, Sox6tm1Vlf/Sox6tm1Vlf (more )
Structure Level Pattern Image Note
TS20: cervical vertebral cartilage condensation Absent 4B Col1a1 Sox5-/-;Sox6-/- Expression was absent as in wild type.
TS20: thoracic vertebral cartilage condensation Absent 4B Col1a1 Sox5-/-;Sox6-/- Expression was absent as in wild type.
TS20: embryo Strong Regionally restricted 4B Col1a1 Sox5-/-;Sox6-/- Expression was intense in tissues surrounding the prevertebral cartilages as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory