Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Pot1atm1.1Tdl
Name:	protection of telomeres 1A; targeted mutation 1.1, Titia de Lange
MGI ID:	MGI:3665331
Synonyms:	POT1aFLOX
Gene:	Pot1a  Location: Chr6:25743939-25809280 bp, - strand  Genetic Position: Chr6, 11.65 cM
Alliance:	Pot1atm1.1Tdl page

Germline Transmission:	Earliest citation of germline transmission: J:112185
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The FRT-flanked STOP cassette was removed from intron 2 via flp mediated recombination, leaving exon 3 flanked with a loxP site and a floxed neo cassette. (J:112185)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pot1a Mutation:	42 strains or lines available

Original:	J:112185 Hockemeyer D, et al., Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell. 2006 Jul 14;126(1):63-77
All:	3 reference(s)