Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Pcp2-cre)3Mdk
Name:	transgene insertion 3, Michael D Koob
MGI ID:	MGI:3664534
Synonyms:	P-CRE-3
Transgene:	Tg(Pcp2-cre)3Mdk  Location: unknown
Alliance:	Tg(Pcp2-cre)3Mdk page

Strain of Origin:

Not Applicable

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Pcp2-cre)3Mdk expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Pcp2   Mutation details: This transgene consists of a 835 bp fragment of the purkinje cell protein 2 5' regulatory region, 1.3 kb of Cre recombinase, and 240 bp of simian virus 40 polyA signal. This transgene expresses cre specifically in Purkinje cells. A transgenic line Tg(Pcp2-cre)1Mdk was also produced but was less effective. (J:112937)

Activity:	Tissue activity of this recombinase allele
Driver:	Pcp2 (species not specified) Summary of all recombinase alleles driven by Pcp2. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:112937 He Y, et al., Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits. J Neurosci. 2006 Sep 27;26(39):9975-82
All:	1 reference(s)