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Gene Expression Data
Assay Details
Assay
Reference: J:83956 Bladt F, et al., The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol Cell Biol. 2003 Jul;23(13):4586-97
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3663632
Gene symbol: Nck1
Gene name: non-catalytic region of tyrosine kinase adaptor protein 1
Reporter: lacZ
Direct Detection
Assay notes: Fixative was 1.6% formaldehyde-0.2% glutaraldehyde.
Results
Specimen 4a: embryonic day 7.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS11: embryo Weak Uniform 4a
TS11: allantois Strong 4a
TS11: extraembryonic component Strong 4a
TS11: head mesenchyme Strong 4a

Specimen 4b: embryonic day 8.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS13: embryo Weak 4b Expression is weak throughout the embryo.
TS13: primitive streak Present Regionally restricted 4b Expression is in the node.
TS13: future brain Present 4b
TS13: neural tube Present 4b
TS13: somite Present 4b
TS13: yolk sac Weak 4b

Specimen 4c: embryonic day 8.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS13: embryo Weak 4c Expression is weak throughout the embryo.
TS13: primitive streak Present Regionally restricted 4c Expression is in the node.
TS13: future brain Present 4c
TS13: neural tube Present 4c
TS13: somite Present 4c
TS13: yolk sac Weak 4c

Specimen 5j: embryonic day 8.5; Nck1tm1Paw/Nck1tm1Paw (more )
Structure Level Pattern Image Note
TS13: embryo Weak 5j Staining is throughout the embryo.

Specimen 6a: embryonic day 10.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Strong Regionally restricted 6a Expression is in motorneurons.
TS17: dorsal root ganglion Strong 6a
TS17: notochord Present 6a
TS17: trunk sclerotome Present 6a
TS17: trunk somite Present 6a

Specimen 6b: embryonic day 10.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS17: peripheral nerve trunk Strong 6b
TS17: tail somite Present 6b
TS17: trunk somite Present 6b

Specimen 6c: embryonic day 10.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS17: common atrial chamber Present 6c

Specimen 6d: embryonic day 10.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS17: arterial system Present 6d
TS17: tail sclerotome Present 6d
TS17: trunk sclerotome Present 6d

Specimen 6e: embryonic day 10.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS17: facial ganglion Strong 6e
TS17: arterial system Present 6e

Specimen 6f: embryonic day 10.5; Nck1tm1Paw/Nck1+ (more )
Structure Level Pattern Image Note
TS17: optic cup inner layer Strong 6f
TS17: arterial system Present 6f


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory