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Gene Expression Data
Assay Details
Assay
Reference: J:99326 Kuhnert F, et al., Dosage-dependent requirement for mouse Vezf1 in vascular system development. Dev Biol. 2005 Jul 1;283(1):140-156
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3663442
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2B: embryonic day 9.5; Vezf1tm1Stmn/Vezf1tm1Stmn (more )
Structure Level Pattern Image Note
TS15: blood vessel Present 2B Expression was detected in the mutant, but vascular phenotypic abnormalities were noted.

Specimen 2E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: blood vessel Present 2E

Specimen 2C: embryonic day 9.5; Vezf1tm1Stmn/Vezf1tm1Stmn (more )
Structure Level Pattern Image Note
TS15: blood vessel Present 2C Expression was detected in the mutant, but vascular phenotypic abnormalities were noted.

Specimen 2F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: blood vessel Present 2F

Specimen 3A: embryonic day 9.5; Vezf1tm1Stmn/Vezf1tm1Stmn (more )
Structure Level Pattern Image Note
TS15: extraembryonic vascular system Present 3A Expression was detected as in wild type.

Specimen 3B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: extraembryonic vascular system Present 3B

Specimen 3C: embryonic day 9.5; Vezf1tm1Stmn/Vezf1tm1Stmn (more )
Structure Level Pattern Image Note
TS15: extraembryonic vascular system Present Regionally restricted 3C (w/ inset) Expression was detected as in wild type embryos, including expression in endothelial cells lining the blood islands.

Specimen 3D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: extraembryonic vascular system Present 3D (w/ inset) Expression was detected in endothelial cells lining blood islands.

Specimen not shown: embryonic day 10.5; Vezf1tm1Stmn/Vezf1tm1Stmn (more )
Structure Level Pattern Image Note
TS17: extraembryonic vascular system Present Expression was detected as in wild type.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: extraembryonic vascular system Present

Specimen 4E: embryonic day 12.5; Vezf1tm1Stmn/Vezf1tm1Stmn (more )
Structure Level Pattern Image Note
TS20: blood vessel Present 4E Expression was detected as in wild type.

Specimen 4F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood vessel Present 4F

Specimen 8G, 8K, 8M, 8N, 8O: embryonic day 13.5; Vezf1tm1Stmn/Vezf1+ (more )
Note: Fig. 8K, 8M, 8N, 8O are higher magnification images of the embryo in Fig. 8G.
Structure Level Pattern Image Note
TS21: blood vessel Present 8K , 8M , 8O , 8G , 8N Expression was detected in embryonic vasculature. The heterozygous mutant displayed hypervascularization that was outlined by the immunostaining.

Specimen 8H, 8L, 8P: embryonic day 13.5 (more )
Note: Fig. 8L and 8P are higher magnification images of the embryo in Fig. 8H.
Structure Level Pattern Image Note
TS21: blood vessel Present 8P , 8H , 8L

Specimen 9: embryonic day 13.5; Vezf1tm1Stmn/Vezf1+ (more )
Note: The data in Fig. 9 is presented in a graph of quantitative morphometric analysis.
Structure Level Pattern Image Note
TS21: blood vessel Present

Specimen 9: embryonic day 13.5 (more )
Note: The data in Fig. 9 is presented in a graph of quantitative morphometric analysis.
Structure Level Pattern Image Note
TS21: blood vessel Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory