Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Igh-6-Cd80)1Gjf
Name:	transgene insertion 1, Gordon J Freeman
MGI ID:	MGI:3656398
Synonyms:	B7-1 transgene, B7-1T Tg, B.B7-1, T.B7-1
Transgene:	Tg(Igh-6-Cd80)1Gjf  Location: unknown
Alliance:	Tg(Igh-6-Cd80)1Gjf page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Igh-6-Cd80)1Gjf expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Cd80 (MGI:101775)   Mutation details: The transgene was constructed with the Cd80 cDNA containing the complete coding region (but lacking the 2' and 5' UTRs) under control of the Igh-6 enhancer and promoter elements. The construct also contained a mutated nonexpressible segment of the human growth hormone gene included to enhance transgene expression. (J:112474)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:112474 Sethna MP, et al., A negative regulatory function of B7 revealed in B7-1 transgenic mice. Immunity. 1994 Aug;1(5):415-21
All:	4 reference(s)