Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(GFAP-cre)1Kdmc
Name:	transgene insertion 1, Ken D McCarthy
MGI ID:	MGI:3655847
Synonyms:	GFAP-cre
Transgene:	Tg(GFAP-cre)1Kdmc  Location: unknown
Alliance:	Tg(GFAP-cre)1Kdmc page

Strain of Origin:

C57BL/6 x C3H

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(GFAP-cre)1Kdmc expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human GFAP (2670) Gfap  (MGI:95697)   Mutation details: A human GFAP promoter was used to drive expression of Cre recombinase, with an intron and polyadenylation signals from the mouse protamine-1 gene. The promoter-cre fragment was surrounded by four copies of a genomic insulator. Cre recombinase expression is restricted to GFAP-positive astrocytes in brain; neurons and oligodendrocytes do not express the Cre protein. (J:108621)

Activity:	Tissue activity of this recombinase allele
Driver:	GFAP (human) Summary of all recombinase alleles driven by GFAP. Comparative matrix view of recombinase activities Alliance human GFAP gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:108621 Casper KB, et al., GFAP-positive progenitor cells produce neurons and oligodendrocytes throughout the CNS. Mol Cell Neurosci. 2006 Apr;31(4):676-84
All:	25 reference(s)