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Gene Expression Data
Assay Details
Assay
Reference: J:105240 Anttonen AK, et al., The gene disrupted in Marinesco-Sjogren syndrome encodes SIL1, an HSPA5 cochaperone. Nat Genet. 2005 Dec;37(12):1309-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3655495
Gene symbol: Sil1
Gene name: SIL1 nucleotide exchange factor
Antibody: anti-SIL1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: This data is pictured in the supplementary material.
Results
Specimen S5a,c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle epithelium Present S5c , S5a
TS20: retina Present S5c , S5a

Specimen S5e: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present S5e There is diffuse expression in the developing cerebral cortex.

Specimen S5g: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: neocortex layer Present S5g Expression is present in cortical neurons.

Specimen S5i,k: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum Present S5i
TS28: cerebellum Purkinje cell layer Present S5i , S5k
TS28: cerebellum white matter Present S5i Expression is present in the glial cells of the white matter.

Specimen not shown: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Occasional immunopositive granule cells are seen.

Specimen S5m,o: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present S5m
TS28: hippocampus CA4 Present S5m
TS28: hippocampus pyramidal cell layer Present S5m
TS28: hippocampus CA2 Present S5m , S5o Expression is somewhat accentuated in region CA3.
TS28: hippocampus CA3 Present S5m , S5o Expression is somewhat accentuated in region CA3.
TS28: dentate gyrus Present S5m


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory