Tg(Igh-V12CH27/Igh-6)6-1Shc
Transgene Detail
|
|
| Symbol: |
Tg(Igh-V12CH27/Igh-6)6-1Shc |
| Name: |
transgene insertion 6-1, Stephen H Clarke |
| MGI ID: |
MGI:3653424 |
| Synonyms: |
6-1, IgPtC, Tg(Igh-V12CH27/Igh6)6-1Shc, V12-Tg, VH12 Tg |
| Transgene: |
Tg(Igh-V12CH27/Igh-6)6-1Shc Location: unknown
|
| Alliance: |
Tg(Igh-V12CH27/Igh-6)6-1Shc page
|
|
| Strain of Origin: |
(C57BL/6 x SJL)F2
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(Igh-V12CH27/Igh-6)6-1Shc expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Igh (MGI:96442) |
|
|
| |
|
Mutation details: An Igh-V12 fragment derived from the PtC-specific lymphoma cell line CH27 was fused to the 5' end of the IgM constant region gene. Four founder lines were established and two of them were characterized. Line 6-1 contains 15-20 copies of the transgene and line 7-2 contains 1-2 copies.
(J:111246)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:111246 Arnold LW, et al., Development of B-1 cells: segregation of phosphatidyl choline-specific B cells to the B-1 population occurs after immunoglobulin gene expression. J Exp Med. 1994 May 1;179(5):1585-95 |
| All: |
15 reference(s) |
|
Analysis Tools
