Gene Expression Data
Assay Details
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Assay
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Reference:
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J:107596
Goodchild RE, et al., Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope. Neuron. 2005 Dec 22;48(6):923-32
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3653368
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Gene symbol:
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Lmnb1
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Gene name:
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lamin B1
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Antibody:
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anti-laminB
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Detection system:
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Secondary antibody coupled to Cy3
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Assay notes:
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Fixative was 4% formaldehyde.
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Results
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Specimen
6A +/+:
embryonic day 18.5
(more  )
Specimen
6A +/+:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Cryosection
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Specimen
6A -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Tor1atm1Wtd/Tor1atm1Wtd
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: ventral grey horn |
Present |
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6A -/-
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Expression in this mutant is the same as in wild-type but this mutant exhibits nuclear envelope abnormalities in large ventral horn neurons.
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Specimen
6C +/+:
embryonic day 18.5
(more )
Specimen
6C +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Cryosection
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Specimen
6C -/-:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Tor1atm1Wtd/Tor1atm1Wtd
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Cryosection
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Analysis Tools