Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dmbx1tm3(cre)Aoh
Name:	diencephalon/mesencephalon homeobox 1; targeted mutation 3, Akihira Ohtoshi
MGI ID:	MGI:3641328
Synonyms:	Dmnx1Cre
Gene:	Dmbx1  Location: Chr4:115772316-115797123 bp, - strand  Genetic Position: Chr4, 53.07 cM
Alliance:	Dmbx1tm3(cre)Aoh page

Germline Transmission:	Earliest citation of germline transmission: J:110604
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Dmbx1tm3(cre)Aoh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Dmbx1 (MGI:2153518)   Mutation details: A vector coding for a splice acceptor, IRES, and Cre protein was inserted into intron 1 via homologous recombination. Cre activity is seen in the embryonic diencephalon and mesencephalon and in the postnatal midbrain, cerebellum, medulla oblongata, and spinal cord. (J:110604)

Activity:	Tissue activity of this recombinase allele
Driver:	Dmbx1 (mouse) Summary of all recombinase alleles driven by Dmbx1. Comparative matrix view of recombinase activities Alliance mouse Dmbx1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dmbx1 Mutation:	20 strains or lines available

Original:	J:110604 Ohtoshi A, et al., Generation and maintenance of Dmbx1 gene-targeted mutant alleles. Mamm Genome. 2006 Jul;17(7):744-750
All:	3 reference(s)