Tg(Tyr-cre/ERT2)13Bos
Transgene Detail
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| Symbol: |
Tg(Tyr-cre/ERT2)13Bos |
| Name: |
transgene insertion 13, Marcus Bosenberg |
| MGI ID: |
MGI:3641203 |
| Synonyms: |
Tyr::CreER, Tyr::CreERT2, Tyr::CreERT2-Bos |
| Transgene: |
Tg(Tyr-cre/ERT2)13Bos Location: unknown Genetic Position: Chr2, Syntenic
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| Alliance: |
Tg(Tyr-cre/ERT2)13Bos page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutations: |
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Insertion, Intergenic deletion
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Tg(Tyr-cre/ERT2)13Bos expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Tyr |
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Mutation details: This transgene consists of a 5.5 kb fragment of the Tyr promoter and a 3.6 kb fragment of the Tyr enhancer driving expression of a tamoxifen-inducible form of cre recombinase. 3 lines were generated which all showed tamoxifen-inducible Cre activity in cutaneous melanocytes. This is a representative record for all 3 lines. Line 13 contains 2 copies of the transgene inserted into chromosome 2 (chr2:129,989,606; NCBI37/mm9) 7.8 kb downstream of Snrpb and 9.6 kb downstream of Tgm6 with a 3 kb deletion at the integration site. In addition, three or more copies of the transgene were integrated on chromosome 2 resulting in ~3 kb deletion of this intergenic region between base pairs 130,160,936 and 130,163,877 [mouse mm10].
(J:110143, J:240920, J:282623)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Tyr
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 12 strains available
Cell Lines: 0 lines available
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| Original: |
J:110143 Bosenberg M, et al., Characterization of melanocyte-specific inducible Cre recombinase transgenic mice. Genesis. 2006 May;44(5):262-7 |
| All: |
152 reference(s) |
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Analysis Tools