Tg(HLA-B)2Mtkg
Transgene Detail
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| Symbol: |
Tg(HLA-B)2Mtkg |
| Name: |
transgene insertion 2, Masafumi Takiguchi |
| MGI ID: |
MGI:3641142 |
| Synonyms: |
Tg(HLA-B3501), Tg(HLAB3501) |
| Transgene: |
Tg(HLA-B)2Mtkg Location: unknown
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| Alliance: |
Tg(HLA-B)2Mtkg page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene comprises a 6.4-kb fragment containing a B*3501 allele of the human major histocompatibility complex, class I, B antigen gene. Surface expression of the transgene product on peripheral blood lymphocytes and spleen cells was demonstrated by flow cytometry with an anti-HLA Class I monoclonal antibody; expression levels were similar to those of endogenous mouse MHC antigens. Western blot analysis revealed high levels of expression in lung, spleen, thymus and skin and low to medium expression in heart and brain.
(J:110794)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:110794 Schonbach C, et al., Identification of HTLV-1-specific CTL directed against synthetic and naturally processed peptides in HLA-B*3501 transgenic mice. Virology. 1996 Dec 1;226(1):102-12 |
| All: |
2 reference(s) |
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Analysis Tools
