Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxctm1Nogu
Name:	homeobox C cluster; targeted mutation 1, Shigeru Noguchi
MGI ID:	MGI:3640654
Gene:	Hoxc  Location: unknown  Genetic Position: Chr15, cytoband F1-F3

Germline Transmission:	Earliest citation of germline transmission: J:61710
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout) Mutation:    Intergenic deletion   Hoxctm1Nogu involves 12 genes/genome features (Hoxc13, Hoxc12, Hotair ...) View all   Mutation details: Targeting constructs for the Hoxc-4 and Hoxc-13 genes were used to put loxP sites into a targeting vector. After electroporation of CCE ES cells with the targeting vector, homologous recombination produced doubly-targeted ES cells. Following introduction of a Cre expressing plasmid, deletion of 130 kb encompassing the Hoxc gene cluster resulted. (J:61710)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	175 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hoxc Mutation:	1 strain or line available

Original:	J:61710 Suemori H, et al., Hox C cluster genes are dispensable for overall body plan of mouse embryonic development. Dev Biol. 2000 Apr 15;220(2):333-42
All:	6 reference(s)